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rabbit phosphocreb cell signaling  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit phosphocreb cell signaling
    Rabbit Phosphocreb Cell Signaling, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 2198 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit phosphocreb cell signaling/product/Cell Signaling Technology Inc
    Average 98 stars, based on 2198 article reviews
    rabbit phosphocreb cell signaling - by Bioz Stars, 2026-03
    98/100 stars

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    ( A ) Kaplan-Meier survival curves of control (N=77), HoxB7-Cre; Pkd1 f/f (N=41), HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f (N=37) and HoxB7-Cre; Ankmy2 f/f (N=37) mice. **, p=0024 by log-rank (Mantel-Cox) test. (B) H&E and whole mount images of P15 kidneys in control, HoxB7-Cre; Pkd1 f/f , HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f , HoxB7-Cre; Ankmy2 f/f mice at P15 in C57BL/6J background. Images of multiple kidneys shown in Figure S3. (C) 2-Kidney to body weight ratios at P15 in HoxB7-Cre; Pkd1 f/f mice were not significantly different from HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f . Both males (black) and females (red) are shown. (D) At P15 cystic index in HoxB7-Cre; Pkd1 f/f kidneys compared to HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f were not significantly different. <t>(E)</t> <t>AQP2/pCREB</t> co-staining in kidney sections at P15 shows comparable nuclear pCREB levels in HoxB7-Cre; Pkd1 f/f animals and HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f cysts. Scale: 50 µm. See also Supplemental Figure 2.
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    ( A ) Kaplan-Meier survival curves of control (N=77), HoxB7-Cre; Pkd1 f/f (N=41), HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f (N=37) and HoxB7-Cre; Ankmy2 f/f (N=37) mice. **, p=0024 by log-rank (Mantel-Cox) test. (B) H&E and whole mount images of P15 kidneys in control, HoxB7-Cre; Pkd1 f/f , HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f , HoxB7-Cre; Ankmy2 f/f mice at P15 in C57BL/6J background. Images of multiple kidneys shown in Figure S3. (C) 2-Kidney to body weight ratios at P15 in HoxB7-Cre; Pkd1 f/f mice were not significantly different from HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f . Both males (black) and females (red) are shown. (D) At P15 cystic index in HoxB7-Cre; Pkd1 f/f kidneys compared to HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f were not significantly different. (E) AQP2/pCREB co-staining in kidney sections at P15 shows comparable nuclear pCREB levels in HoxB7-Cre; Pkd1 f/f animals and HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f cysts. Scale: 50 µm. See also Supplemental Figure 2.

    Journal: bioRxiv

    Article Title: Kidney cystogenesis in embryonic- and adult-onset ADPKD is suppressed from lack of adenylyl cyclase targeting to cilia

    doi: 10.1101/2025.05.27.656198

    Figure Lengend Snippet: ( A ) Kaplan-Meier survival curves of control (N=77), HoxB7-Cre; Pkd1 f/f (N=41), HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f (N=37) and HoxB7-Cre; Ankmy2 f/f (N=37) mice. **, p=0024 by log-rank (Mantel-Cox) test. (B) H&E and whole mount images of P15 kidneys in control, HoxB7-Cre; Pkd1 f/f , HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f , HoxB7-Cre; Ankmy2 f/f mice at P15 in C57BL/6J background. Images of multiple kidneys shown in Figure S3. (C) 2-Kidney to body weight ratios at P15 in HoxB7-Cre; Pkd1 f/f mice were not significantly different from HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f . Both males (black) and females (red) are shown. (D) At P15 cystic index in HoxB7-Cre; Pkd1 f/f kidneys compared to HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f were not significantly different. (E) AQP2/pCREB co-staining in kidney sections at P15 shows comparable nuclear pCREB levels in HoxB7-Cre; Pkd1 f/f animals and HoxB7-Cre; Pkd1 f/f ; Ankmy2 f/f cysts. Scale: 50 µm. See also Supplemental Figure 2.

    Article Snippet: Sections were incubated with primary antibodies against the following antigens; overnight at room temperature or 4C: Acetylated tubulin (T6793; Sigma mouse IgG2b, 1:500), AQP2 (SC515770, Santa Cruz Biotechnology, mouse IgG1, 1:500), Ki67 (ab16667, Abcam, 1:500), pCREB (9198S; Cell Signaling, 1:500).

    Techniques: Control, Staining